From Points West (Utica/Syracuse/Rochester) – NYS Thruway I-90 East to Exit 29. NY-10 South to Cobleskill. At junction of NY-10/NY-7/NY-145, follow NY-7 East/NY-145 South (Left at light in center of town). Grapevine Farms is 2.0 miles on the left.

From Points West (Oneonta/Binghamton) – I-88 East to Exit 22. Left at end of ramp, left at light onto NY-7 West. Grapevine Farms is 1.3 miles on the right. From Points East (Albany/Boston) – NYS Thruway I-90 West (towards Buffalo) to Exit 25A. I-88 West to Exit 22. Right at end of ramp, left at light onto NY-7 West. Grapevine Farms is 1.3 miles on the right.

From Points North of Albany (Saratoga/Lake George/Plattsburgh) – I-87 South to NYS Thruway I-90 West (towards Buffalo) to Exit 25A. I-88 West to Exit 22. Right at end of ramp, left at light onto NY-7 West. Grapevine Farms is 1.3 miles on the right.

From Points South (Catskill, Lower Hudson Valley, New York City) – NYS Thruway I-87 North to Exit 21. NY-23 West to NY-145 North. At NY-7 - left at light onto NY-7 West. Grapevine Farms is 1.3 miles on the right.